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| c. 1450 |
| | | Coffee, derived from wild plants in Ethiopia, is cultivated in Arabia | |
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| c. 1480 |
| | | The name of Constantinople changes to Istanbul, a word based on the everyday Greek name for the city | |
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| 1497 |
| | | Savonarola, in the carnival before Lent, urges the people of Florence to throw playing cards and lewd images on a great bonfire of vanities | |
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| 1498 |
| | | The Florentine mob, weary of puritanism, attacks the convent of San Marco and drags Savonarola away to be hanged and burnt | |
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| 1525 |
| | | Luther, a former friar, marries Catherine von Bora, a former nun who has just emerged from her convent | |
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| c. 1585 |
| | | The English artist John White paints the everyday life of the Secotan Indians of America | |
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| c. 1590 |
| | | Serfdom is introduced in Russia by Boris Godunov, whose measures tie the peasants to the land | |
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| 1596 |
| | | A flush toilet is illustrated in an English pamphlet, The Metamorphosis of Ajax by John Harrington | |
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| 1604 |
| | | The British king James I launches a blistering attack on the smoking of tobacco, which he considers a loathsome custom | |
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| 1616 |
| | | Pocahontas fascinates Londoners when she arrives with her husband to publicize Jamestown | |
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